Commentary on Genesis, Vol. II / Luther on Sin and the Flood

Although the present aspect of those places does not altogether bear out that conclusion, the devastations of the mighty deluge were such as to change fountains, rivers and mountains; and it is quite possible that on the site which was afterward Calvary, the place of Christ's sacrifice for the world's sin, there stood the tree of the knowledge of good and evil, the same spot being marked by the death and ruin wrought by Satan and by the life and salvation wrought by Christ.

Note the difference between the several ages of the world! The primeval age was the most excellent and holy